Skin diseases specific to pregnancy consist of a number of diseases with different characteristics that are not well defined and are seen only during pregnancy and the post-pregnancy period. Although there are various classifications, today it is divided into 4 groups.
*Intrahepatic cholestasis of pregnancy
*Pemphigoid gestationes
*Polymimorphic eruption of pregnancy
*Atopic eruption of pregnancy
INTRAHEPATIC CHOLESSTASIS OF PREGNANCY:
In people with genetic predisposition, late pregnancy; A skin rash, characterized by severe itching, that occurs during the pregnancy period (after 30 weeks). non-forming recycled materials. is a bile duct obstruction. Fetal stress, premature birth, death for the baby It creates risks such as birth.
Risk factors:
Hepatitis C, advanced maternal age, multiple pregnancy, gallstones, previous gallbladder surgery
Reason:
Due to the disorder in the metabolism of bile acids from the maternal bloodstream, the level of bile acids in the blood increases, accumulates in the skin and causes itching, and may lead to vitamin K deficiency as a result of increased fat excretion in the mother.
Features
30. It starts after a week
The rash of itching. there is no
The most common palm It starts with itching inside and on the soles of the feet, then itching appears on the outer surface of the arms and legs and then spreads to the body. Jaundice may appear in 10-20% of patients within 1-4 weeks.
Diagnosis
It is done with blood tests. Serup ALP level increased.
Treatment:
Ursedeoxycholic acid 10-60 mg/day is used.
Course
Most of it regresses 24-48 hours after birth. jaundice may last 1-2 weeks. It may occur again in repeated pregnancies and birth control pill use.
PEMGIGOID GESTATIONS:
Although it is usually seen in the 2nd and 3rd trimesters (average 21st week), it can also be seen in the first trimester and after pregnancy, and is a disease caused by a disorder in the body's immune system. It most often starts around the navel and then spreads to the trunk, arms and legs. It initially starts as a urticaria-like swelling, and then bubbles containing small liquids form on these swellings.
Course
The severity usually decreases in the last 1-2 weeks of pregnancy and flares up again during and after birth.
Recurrence may occur in subsequent pregnancies, and the possibility of it starting at earlier times is high.
It may cause placental insufficiency and lead to the development of a low birth weight baby.
Diagnosis
Detected by biopsy
Treatment:
Topical cortisone treatment is given in mild cases, and oral cortisone treatment is given in severe cases.
POLYMORPHIC ER&UUMLOPSION OF PREGNANCY
They are severe itchy red bumps that form in cracks on the body. It is usually seen in first-time pregnant women and in the 3rd trimester of pregnancy (35th week on average). It is observed more frequently in multiple pregnancies, polyhydramnios and excessive weight gain, which increase the tension of the abdominal wall.
Cruising
Usually does not exceed 6 weeks. It does not recur in subsequent pregnancies. It does not pose a risk to the baby.
Treatment:
Topical cortisone creams and moisturizers.
ATOPIC ECZEMA OF PREGNANCY
It often begins in the 2nd trimester. In 2/3 of the cases, the face, neck, décolleté, inner arms and legs are affected. redness on the face; It is seen as swelling in 1/3 of the cases.
Course
It often recurs in other pregnancies. It does not pose a risk to the baby.
Treatment:
They are anti-itch creams and moisturizers.